In the context of the EPOXI mission, at the beginning of November 2010 the comet 103P/Hartley 2 was visited by the Deep-Impact spacecraft, that passed at only 700 km from its nucleus. To connect spatial small scales, as seen from the spacecraft, to large ones, the comet was the target of a wide campaign of remote observations involving many observatories around the world and from space. In this framework we observed the comet at the beginning of September 2010 with the Italian Telecopio Nazionale Galileo (TNG), at the beginning of November 2010, and January 2011 with the ESO NTT telescope. Here we will report the results obtained in November, during the spacecraft fly-by.