The local galaxy Science Advisory Group (SAG 2) in the Herschel/SPIRE consortium, has constructed a Guaranteed Time Key Program using the PACS and SPIRE insruments to obtain 60 to 550 micron photometry of a statistically significant sample of 51 dwarf galaxies in our local universe chosen to cover an impressivly broad range of physical conditions. Here we propose the necessary complementary IRAC, MIPS and IRS Spitzer observations which together with the Herschel GT database will provide a rich database to the community to perform the dust and gas analyses in unprecedented detail in low metallicity galaxies ranging between 1/50 to 1 solar metallicity. Due to their chemical youth, and to the extreme conditions they experience, low metallicity environments constitute a keystone to understand dust evolution. The primary goal of this combined Herschel and Spitzer project is to study in details the physical processes at play within the ISM of these galaxies. We will take advantage of the powerful combination of Spitzer, Herschel and ancillary data to decompose the SED into the emission coming from the main phases of the ISM. Such a decomposition will provide reliable estimate of the abundances of the principal dust species, as a fonction of metallicity and physical conditions. These results will be exploited to compare the various evolutionary processes affecting the dust content of galaxies. All these outstanding scientific advances will be the true legacy value that this project brings to the community.